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September 10, 2002

First Employment of an Air Push System for an OTC drug
Pabron Cough Medicine <Stick Jelly> Launched

Pabron Ace Granule image

Taisho Pharmaceutical Co., Ltd. (President: Akira Uehara) released on October 1 a new cough medicine formulation, "Pabron Cough Medicine <Stick Jelly>," that is designed to be easy for users to ingest.

Pabron Cough Medicine <Stick Jelly> is a cough medicine with a new formulation that is the first over-the-counter drug to employ an air push system*.
Jelly-type cough medicines have begun to be approved in the current period. Among them, our product is characterized by a formulation that ensures smooth administration. The medicine is conveniently packaged into individual dosages, eliminating the need for measurement, thus, you no longer need to worry about spilling cough medicine, and can keep it clean. You also enjoy its portability.

Five active components, including dihydrocodeine phosphate, certainly work on cough and sputum. Our original masking technology successfully suppresses the bitterness of bitter components, converting the taste into a coffee flavor.

Taisho Pharmaceutical began selling Pabron as a cough medicine in1927.
Since then, we have responded to the needs of consumers by expanding on this series, changing formulas and developing new drugs as a brand of general cold medicines.

Air push system
Jelly can be pushed out by pressing an air layer part at the bottom of a package of stick where air is included.

[Why Stick Jelly for a Cough Medicine?]
A jelly formulation has the following advantages: (1) It does not get caught in the throat; (2) It does not spill; (3) It does not choke the user; (4) It can be taken while lying down; and (5) It can be taken without water.
People suffering from a persistent cough can easily choke on medicine. Stick jelly can be readily taken, even with a very bad cough. This is a new-formulation, a portable drug which eliminates the need to measure servings, and helps relieve you from sudden attacks.

[Industry Trends]
The industry has not really been allowed to sell medicines that can be comfortably taken or medicines in easy-to-take formulations, because of the risk of overdose. However, it is becoming easier to research, develop and sell easy-to-take formulations because of elevated awareness of self-medication among consumers and the promotion of appropriate use of such medicines by patients.
Consumers are increasingly welcoming those medicines that have recently been developed, being improved in ease of administration based on the special characteristics of the formulations as well as on its essential efficacy, including a smoking cessation gum, a jelly formulation for cough medicine and melt-in-the-mouth tablets.
The development of medicines with devised formulations will continue to be required, taking into account the needs of consumers, including the elderly. 

[Reasons for Using the Name "Pabron"]
The name Pabron consists of "pan" (meaning "all") and "bronchus" (meaning "a bronchial tube").
The name reflects the aim that the drug work on the entire bronchus.
The history of Pabron began in 1927 when it was launched as an antitussive, expectorant drug.

Product Features
1. Coffee-flavored jelly formulation which can be smoothly swallowed
2. Measurement-saving package divided into each dosage. Hygienic and convenient to carry with.
3. This can be easily taken anywhere, even without water.
4. Five active components surely work on cough and sputum.

Product Specifications
Product name Pabron Cough Medicine <Stick Jelly>
Suggested retail price ¥1,200 for 6 portions
Active ingredients Three portions (18g) contain:
Dihydrocodein phosphate 30mg
Guaifenesin 180mg
dl-methylephedrine hydrochloride 75mg
Carbinoxamine maleate 12mg
Platycodon fluidextract 400mg
Indications Cough and sputum
Dosage One portion per time, three times daily for persons aged 15 and older
Melt the jelly in your mouth, if possible, within 30 minutes after a meals.
Date of release October 1, 2002
Expected sales ¥500million