After carefully considering the needs of medical professionals, only those drugs that have been confirmed to be worthy of development are passed on to the Drug Metabolism & Toxicology Research Center. At this stage, basic research is conducted to check the drug's efficacy, safety, and mechanisms, followed by a rigorous evaluation of all aspects of the drug. The drug then undergoes repeated clinical testing in humans to demonstrate its efficacy and safety, and a request for approval is filed with the Ministry of Health and Welfare. After this approval is received and the product is launched on the market, the process continues with further basic research and clinical testing and the gathering of market data to find ways to make the drug even better.